What Are the Long-Term Histological Effects of Chronic UV Exposure?
Chronic UV exposure leads to long-term histological changes in the skin, often referred to as photoaging. These changes include the breakdown of collagen and elastin fibers in the dermis, leading to wrinkles and loss of skin elasticity. There is also an increased risk of developing various types of skin cancer due to the accumulation of DNA damage over time. Histologically, photoaged skin may exhibit elastosis, characterized by an abundance of abnormal elastic fibers, and a general degradation of the skin's structural integrity.