Ectoderm: This layer is crucial for forming the central nervous system (brain and spinal cord), peripheral nervous system, epidermis (skin), hair, nails, and sensory organs. Mesoderm: It is responsible for developing the musculoskeletal system (bones and muscles), circulatory system (heart and blood vessels), excretory system (kidneys), and reproductive system. Endoderm: This layer forms the epithelial lining of the gastrointestinal and respiratory tracts, as well as associated organs like the thyroid, liver, and pancreas.