What Are the Histological Signs of Vitamin Deficiencies?
Different vitamins have distinct roles in cellular processes, and their deficiencies can lead to characteristic histological changes: - Vitamin C Deficiency: Leads to scurvy, which is marked by weakened collagen fibers in connective tissues. Under the microscope, one might notice poorly formed collagen and hemorrhages. - Vitamin D Deficiency: Results in rickets in children and osteomalacia in adults. Histologically, this manifests as poorly mineralized bone matrix and increased amounts of unmineralized osteoid. - Vitamin B12 Deficiency: Causes megaloblastic anemia, where histological examination reveals enlarged and abnormal hematopoietic cells in the bone marrow.
