What are the Histological Implications of Caspase 9 Activation?
In histology, the activation of Caspase 9 can be observed in various pathological conditions where apoptosis plays a significant role. This includes neurodegenerative diseases such as Alzheimer's and Parkinson's, where excessive apoptosis leads to the loss of neuronal cells. Similarly, in cancer, dysregulation of Caspase 9 activity can result in either resistance to apoptosis, contributing to tumor growth, or excessive cell death, leading to tissue damage.
