What are the histological features of EBV-associated cancers?
In Hodgkin lymphoma, EBV is often found in the neoplastic Reed-Sternberg cells, which are large cells with prominent nucleoli and a characteristic "owl-eye" appearance. In nasopharyngeal carcinoma, EBV is associated with undifferentiated carcinoma, which shows a syncytial growth pattern of tumor cells with a dense lymphoid infiltrate.
