What Are the Histological Differences Between Grades of Sprains?
Ligament sprains are classified into three grades based on severity:
- Grade I (Mild): Involves microscopic tears or stretching of the ligament fibers. Histologically, there may be minimal disruption of the collagen fibers with a mild inflammatory response.
- Grade II (Moderate): Characterized by partial tearing of the ligament. Histologically, there is a more pronounced disruption of the collagen fibers, moderate inflammation, and some degree of hemorrhage.
- Grade III (Severe): Involves a complete tear or rupture of the ligament. Histologically, there is a complete disruption of the collagen architecture, significant inflammation, and extensive hemorrhage.
