What Are the Consequences of Defective Cytokinesis?
Defects in cytokinesis can lead to several issues, including:
- Multinucleation: Failure to complete cytokinesis results in cells with multiple nuclei, which can disrupt normal cellular functions and lead to tumorigenesis.
- Aneuploidy: Incomplete or improper division of chromosomes during cytokinesis can cause an abnormal number of chromosomes, contributing to various genetic disorders.
- Developmental Defects: In multicellular organisms, defective cytokinesis can impair development and tissue formation, leading to severe morphological abnormalities.
