What are the Clinical Relevance and Research Applications?
Understanding the structure and function of the fibrillar center has significant implications in both clinical and research settings. Aberrations in nucleolar organization and function are linked to various diseases, including cancer and neurodegenerative disorders. Researchers study the fibrillar center to gain insights into the mechanisms of ribosome biogenesis and its regulation. Targeting the nucleolus and its components, including the fibrillar center, is an emerging strategy in the development of novel therapeutic approaches.
