What Are the Clinical Implications of Sodium Potassium Pump Dysfunction?

Dysfunction of sodium-potassium pumps can have significant clinical implications. For instance, mutations in the genes encoding these pumps can lead to conditions such as familial hemiplegic migraine and certain forms of epilepsy. In cardiac tissue, impaired pump function can contribute to arrhythmias and heart failure. Understanding the histological context of these pumps helps in diagnosing and developing treatments for these conditions.