What Are the Clinical Implications of PNMT Dysregulation?
Dysregulation of PNMT can lead to a variety of clinical conditions. Overproduction of epinephrine may result in disorders such as pheochromocytoma, a tumor of the adrenal medulla. Conversely, insufficient PNMT activity can impair the body's ability to respond to stress, leading to conditions such as adrenal insufficiency.
