In clinical histology, CD61 is a significant marker for diagnosing and monitoring certain hematological and vascular conditions. For instance, elevated levels of CD61-positive megakaryocytes or platelets can indicate disorders such as essential thrombocythemia or chronic myelogenous leukemia. Moreover, aberrant expression of CD61 in endothelial cells may be associated with angiogenesis in tumors, making it a potential target for cancer therapies.
