While stem cell therapy holds great promise, it faces several challenges:
Immune Rejection: Allogeneic stem cells may be recognized as foreign by the recipient's immune system, leading to rejection. Tumorigenicity: There is a risk that stem cells may form tumors if they continue to proliferate uncontrollably. Ethical Issues: The use of embryonic stem cells raises ethical concerns, leading to stringent regulations and restrictions. Technical Challenges: Efficiently directing stem cells to differentiate into the desired cell type and ensuring their integration and function within the target tissue are significant technical hurdles.
