What are the challenges in studying GABAergic neurons?
Studying GABAergic neurons presents several challenges:
- Heterogeneity: GABAergic neurons are highly diverse, with various subtypes that have different functions and molecular markers. - Technical Difficulty: Techniques like electron microscopy and in situ hybridization require specialized equipment and expertise. - Dynamic Changes: GABAergic signaling is highly dynamic and can change in response to various physiological and pathological conditions, making it difficult to study in a static histological context.