signal detection

What are the Challenges in Signal Detection?

Despite advancements, signal detection in histology faces several challenges:
1. Tissue Heterogeneity: The complex and heterogeneous nature of tissues can make it difficult to distinguish specific signals from background noise.
2. Technical Variability: Variations in sample preparation, staining, and imaging can affect the consistency and reproducibility of results.
3. Quantification: Quantifying signals accurately can be challenging, especially when dealing with overlapping signals or low-abundance targets.

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