What are the Challenges in Allogeneic Stem Cell Transplants?
One of the primary challenges in allogeneic stem cell transplants is the risk of immune rejection and GVHD. The recipient's immune system may recognize the transplanted cells as foreign and attack them. Histological analysis is vital in detecting early signs of rejection or GVHD, allowing for timely intervention. Additionally, ensuring the compatibility of donor and recipient through histocompatibility testing reduces the risk of complications.