What are the Challenges and Limitations of RNAi in Histology?
Despite its potential, RNAi faces several challenges: - Off-Target Effects: siRNA can sometimes bind to non-target mRNA, causing unintended gene silencing. - Delivery: Efficient delivery of RNAi molecules to specific tissues remains a significant hurdle. - Stability: RNAi molecules can be unstable and may degrade before reaching their target.