Mutagenesis can be caused by a variety of factors: - Chemical Mutagens: Substances like benzene, formaldehyde, and certain drugs can cause mutations by altering the DNA structure. - Physical Mutagens: Radiation from X-rays, UV light, and radioactive materials can induce mutations by causing breaks in DNA strands. - Biological Mutagens: Some viruses can integrate their genetic material into the host genome, causing mutations.