What are the Applications of Transgenic Models in Histology?
Transgenic models have wide-ranging applications in histology: 1. Disease Modeling: They are used to create models of human diseases, such as cancer, Alzheimer's disease, and muscular dystrophy, allowing for detailed histological analysis. 2. Gene Function Studies: By overexpressing or knocking out specific genes, researchers can study their roles in tissue development and function. 3. Tracing Cell Lineages: Transgenic models with reporter genes, like GFP, enable tracing of cell lineages and understanding cell fate decisions during development.
