One of the primary advantages of MRM is its non-destructive nature. Traditional histological methods often require slicing and staining tissues, which can alter or damage the sample. MRM, on the other hand, allows for the examination of intact tissues, preserving their natural state. This is particularly valuable for studying delicate tissues like the brain or embryo.
Another benefit is the ability to acquire three-dimensional datasets. Unlike histological slices that offer only two-dimensional views, MRM can reconstruct the entire volume of the tissue, providing a comprehensive understanding of its microarchitecture.