What Are the Advantages and Limitations of Warthin-Starry Stain?
The primary advantage of the Warthin-Starry stain is its high sensitivity in detecting certain bacteria. However, it also has several limitations:
Specificity: While it is sensitive, it may not be specific, as non-target microorganisms can also reduce silver and appear stained. Technical Complexity: The procedure is technically demanding and requires precise control of staining conditions to achieve optimal results. Background Staining: Excessive background staining can sometimes obscure microorganisms, making interpretation challenging.