Cell shape changes occur in various contexts, including:
Epithelial to Mesenchymal Transition (EMT): Epithelial cells lose their polarity and adhesion properties to become mesenchymal stem cells, which are more mobile. Neuronal Polarization: Neurons undergo polarization to form axons and dendrites. Immune Cell Activation: Immune cells like macrophages and neutrophils change shape to move towards infection sites. Wound Healing: Fibroblasts change shape to migrate into the wound and produce ECM components for tissue repair.