What Are Some Commonly Used Radioactive Isotopes in Histology?
Several radioactive isotopes are commonly used in histology, including:
Tritium (³H): Often used in autoradiography and ISH, tritium is a low-energy beta-emitter that labels nucleotides and amino acids. Carbon-14 (¹⁴C): A beta-emitter used in metabolic studies and tracing biochemical pathways. Phosphorus-32 (³²P): A high-energy beta-emitter used to label nucleic acids and study DNA synthesis. Sulfur-35 (³⁵S): Employed in protein synthesis studies by incorporating into amino acids like methionine and cysteine.