What are Some Clinical Implications of SNARE Proteins?
Dysfunction in SNARE proteins is linked to various neurological disorders. For example, mutations in SNARE proteins can disrupt neurotransmitter release, leading to conditions such as botulism and tetanus. Moreover, SNARE protein abnormalities are implicated in neurodegenerative diseases like Alzheimer's and Parkinson's disease. Understanding SNARE proteins at the histological level can therefore provide insights into the pathogenesis of these disorders and potential therapeutic targets.