What are Chromosomal Aberrations and How are They Detected?
Chromosomal aberrations are structural or numerical changes in chromosomes that can lead to genetic disorders. These aberrations include deletions, duplications, inversions, translocations, and aneuploidies. Techniques like G-banding, FISH, and SKY are commonly used to detect these abnormalities. For example, Down syndrome is caused by an extra copy of chromosome 21, detectable through karyotyping or FISH.
