Several methods are used to assess the molecular integrity of tissue samples:
Electrophoresis:Gel electrophoresis can be used to check the integrity of DNA and RNA by evaluating the presence of intact or degraded fragments. Spectrophotometry: Measuring absorbance ratios (A260/A280) can provide information on the purity and concentration of nucleic acids. RIN Score: The RNA Integrity Number (RIN) is a standardized metric that evaluates RNA quality. A high RIN score indicates good RNA integrity.