How is the Smooth Endoplasmic Reticulum Visualized in Histology?
The SER can be challenging to visualize due to its lack of ribosomes and relatively homogenous appearance. However, it can be identified using electron microscopy, where it appears as a network of tubules and vesicles. Specific staining techniques, such as the use of osmium tetroxide, can enhance the contrast and help in distinguishing the SER from other cellular structures.
