How is the DNA Double Helix Visualized in Histology?
In histology, the study of tissues at the microscopic level, the DNA double helix itself is too small to be directly visualized using standard light microscopy. Instead, histologists often use various staining techniques, such as Hematoxylin and Eosin (H&E) staining, to highlight cell nuclei where DNA is densely packed. More advanced techniques, like immunohistochemistry and fluorescence in situ hybridization (FISH), can be used to label specific DNA sequences or to identify genetic abnormalities.