Histological techniques are essential for studying neuroplasticity. Microscopy, especially confocal and two-photon microscopy, allows for high-resolution imaging of neuronal structures and synapses. Fluorescent labeling techniques, such as immunohistochemistry and in situ hybridization, enable the visualization of specific proteins and mRNA within neurons.
Electron microscopy provides ultrastructural details of synapses and dendritic spines, revealing changes in synaptic morphology. Additionally, tracing techniques using dyes or genetic markers can map neural circuits and track changes in connectivity.
