The mitotic rate is typically measured by examining histological sections of tissue under a microscope. The steps include:
Tissue Preparation: The tissue sample is fixed, embedded in paraffin, and sliced into thin sections. Staining: The sections are stained using dyes such as hematoxylin and eosin (H&E) to highlight cellular structures. Counting Mitotic Figures: Pathologists count the number of cells in mitosis (mitotic figures) in a specific area, often per high-power field (HPF).
