Lymphoma is a type of hematological malignancy that originates in the lymphoid tissue. Histological examination of lymph node biopsies is pivotal in diagnosing lymphoma. Hodgkin lymphoma is characterized by the presence of Reed-Sternberg cells, which are large, abnormal lymphocytes. In contrast, non-Hodgkin lymphoma shows a more diverse histological pattern with different types of malignant lymphocytes.