Diagnosis is typically made through a combination of imaging studies, such as MRI or CT scans, and histological analysis of a biopsy sample. Immunohistochemistry can be employed to delineate astrocytic origin by using markers like GFAP (glial fibrillary acidic protein). Additionally, genetic testing might be conducted to identify mutations in genes such as IDH1 and TP53, which are often implicated in these tumors.