In histology, DMEM is commonly used during the preparation and maintenance of tissue samples. For example:
During tissue sectioning, cells are often cultured in DMEM to ensure they remain viable and metabolically active. In immunohistochemical staining, cells and tissues are preserved in DMEM to maintain antigenicity and improve staining quality. DMEM is also used in live-cell imaging to provide a nutrient-rich environment that supports cell viability and function.