The synthesis of Collagen Type I involves several steps. Initially, collagen is synthesized as a larger precursor molecule called procollagen within the fibroblasts. Procollagen is then secreted into the extracellular space, where it undergoes enzymatic processing to remove the propeptides, forming mature collagen molecules. These molecules spontaneously assemble into fibrils and fibers, which are then cross-linked to enhance their stability and strength.
