In addition to the pancreas, liver, kidneys, and vascular system, type 2 diabetes can impact other organs. For instance, diabetic retinopathy involves changes in the retinal microvasculature leading to hemorrhages, exudates, and in severe cases, retinal detachment. Peripheral neuropathy is another common complication, where nerve fibers show segmental demyelination and axonal degeneration, leading to impaired sensation and pain.