How Does Transferrin Receptor Interaction Affect Cellular Iron Uptake?
Cells take up iron through a process mediated by the transferrin receptor (TfR). Transferrin binds to TfR on the cell surface, and the complex is internalized via endocytosis. Inside the cell, iron is released from transferrin and utilized, while the transferrin-TfR complex is recycled back to the cell surface. This interaction is vital for cellular iron uptake and is a key focus in histological studies of iron metabolism.
