How Does the Proliferative Zone Contribute to Bone Healing?
In the event of a bone fracture, the proliferative zone plays a significant role in the healing process. The periosteum, which contains a layer of progenitor cells similar to those in the proliferative zone, is activated to produce new chondrocytes and osteoblasts. These cells migrate to the injury site, facilitating the formation of a cartilage callus that is eventually replaced by bone tissue.