Improper tissue size can significantly affect the diagnostic process:
Incomplete Fixation: Larger tissues may not be adequately fixed, leading to autolysis and degradation. Staining Irregularities: Uneven staining can obscure cellular details, complicating diagnosis. Section Quality: Thick sections can result in overlapping cells, while thin sections may tear easily. Data Accuracy: Measurements and observations may be inaccurate, affecting research findings.