How Does FTLD Differ from Other Neurodegenerative Diseases Histologically?
FTLD can be distinguished from other neurodegenerative diseases such as Alzheimer's disease based on histological findings. While Alzheimer's disease is characterized by amyloid plaques and neurofibrillary tangles, FTLD shows different types of protein inclusions such as tau, TDP-43, or FUS. The pattern and distribution of neuronal loss and gliosis also vary between these conditions.
