How Do Stromal Components Interact with Parenchymal Cells?
Stromal components and parenchymal cells engage in dynamic interactions that are crucial for tissue function and homeostasis. The ECM provides structural support and regulates cell behavior through biochemical and mechanical signals. Fibroblasts and immune cells secrete growth factors and cytokines that influence parenchymal cell proliferation, differentiation, and survival. Blood vessels and nerve fibers ensure that parenchymal cells receive adequate nutrients, oxygen, and regulatory signals.