How Do Pacemaker Cells Generate Electrical Impulses?
Pacemaker cells have the unique ability to generate spontaneous electrical impulses due to their unstable resting membrane potential. This is primarily due to the presence of "funny" currents (If) associated with HCN channels. These channels allow an influx of sodium and potassium ions, gradually depolarizing the cell until it reaches the threshold potential, triggering an action potential.
