How do Gray and White Matter Differ Histologically?
In histological sections, gray and white matter can be easily distinguished due to their differences in cellular composition and color. Gray matter appears darker due to the high density of neuronal cell bodies, while white matter appears lighter because of the lipid-rich myelin sheath.
- Staining Techniques: Techniques such as Nissl staining highlight the presence of Nissl bodies in neurons, emphasizing the density of cell bodies in gray matter. Myelin stains, such as Luxol Fast Blue, are used to visualize the myelinated fibers in white matter. - Structural Organization: Gray matter is organized into layers or nuclei, while white matter is organized into tracts or columns.
