When a B cell encounters an antigen that matches its BCR, it becomes activated. This activation process includes several steps:
Antigen Binding: The BCR binds to a specific antigen. Internalization and Processing: The antigen is internalized, processed, and presented on the B cell's surface via MHC Class II molecules. T-Cell Interaction: Helper T cells recognize the antigen-MHC complex and provide necessary co-stimulatory signals. Clonal Expansion: The activated B cell proliferates and differentiates into plasma cells and memory B cells.
