How Do Atomic Interactions Affect Histological Staining?

Histological staining techniques rely on atomic interactions between dyes and tissue components. For instance, hematoxylin binds to acidic structures like nucleic acids through ionic and hydrogen bonds, staining them blue. Conversely, eosin binds to basic structures, such as cytoplasmic proteins, through similar interactions, staining them pink. These staining patterns are crucial for differentiating and visualizing various tissue components under the microscope.