1. Endothelial Cells: ARBs promote endothelial cell function and integrity, reducing inflammation and oxidative stress, which can be seen as improved endothelial cell morphology under histological examination. 2. Smooth Muscle Cells: By inhibiting Angiotensin II, ARBs prevent the proliferation and hypertrophy of smooth muscle cells in vessel walls, leading to thinner and more elastic arteries. 3. Cardiomyocytes: ARBs help in reducing hypertrophy and apoptosis of cardiomyocytes, which can be observed as smaller cell size and less cell death in cardiac tissue samples.