arbs

How do ARBs Affect Cellular Structures?

ARBs impact cellular structures in multiple ways:
1. Endothelial Cells: ARBs promote endothelial cell function and integrity, reducing inflammation and oxidative stress, which can be seen as improved endothelial cell morphology under histological examination.
2. Smooth Muscle Cells: By inhibiting Angiotensin II, ARBs prevent the proliferation and hypertrophy of smooth muscle cells in vessel walls, leading to thinner and more elastic arteries.
3. Cardiomyocytes: ARBs help in reducing hypertrophy and apoptosis of cardiomyocytes, which can be observed as smaller cell size and less cell death in cardiac tissue samples.

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