How Do Amino Acid Metabolism Disorders Affect Tissues?
Disorders in amino acid metabolism can lead to significant tissue abnormalities. For instance, in Phenylketonuria (PKU), the inability to metabolize phenylalanine results in its accumulation, which can cause brain damage and cognitive impairment. In histological studies, such metabolic disorders are often identified by examining tissue samples for abnormal protein accumulation and cellular damage.
