Pigment granules are typically visualized using special histological stains and microscopy techniques. For example, Hematoxylin and Eosin (H&E) staining can reveal the presence of melanin and hemosiderin, while Periodic Acid-Schiff (PAS) staining can highlight lipofuscin granules. Electron microscopy can also be used to study the ultrastructure of pigment granules in greater detail.
