Traditional histological staining methods often lack specificity and sensitivity. Nanoparticles offer an advanced alternative: 1. Fluorescent Labeling: Quantum dots are semiconductor nanoparticles that emit fluorescent light when excited. They can be conjugated with antibodies to label specific proteins in tissues, providing high sensitivity and specificity. 2. Metal Nanoparticles: Gold and silver nanoparticles are used in immunohistochemistry to enhance the detection of antigens. These nanoparticles can be visualized using electron microscopy, providing high-resolution images of tissue sections.
