How are Monoclonal and Polyclonal Antibodies Developed?
Monoclonal antibodies are produced from a single clone of B cells and are specific to one epitope of an antigen. They are generated using hybridoma technology, where B cells are fused with myeloma cells to create a hybrid cell line. Polyclonal antibodies, on the other hand, are produced by immunizing an animal with an antigen, resulting in a mixture of antibodies that recognize multiple epitopes.
