How Are Ligand-Receptor Interactions Studied in Histology?
Histologists employ various techniques to study these interactions:
Immunohistochemistry (IHC): Uses antibodies to detect specific proteins in tissues. Fluorescence in situ hybridization (FISH): Detects specific nucleic acid sequences to study gene expression and localization. Autoradiography: Uses radioactive ligands to visualize receptor distribution. Confocal microscopy: Provides high-resolution images of ligand-receptor interactions in cells and tissues.