How Are Histological Techniques Used in Therapy Development?

Several histological techniques are employed in therapy development:

Immunohistochemistry (IHC): This technique uses antibodies to detect specific proteins in tissues, helping to identify disease markers and evaluate the efficacy of targeted therapies.
In Situ Hybridization (ISH): ISH detects specific nucleic acid sequences within tissues, providing information on gene expression patterns and aiding in the development of gene-based therapies.
Histopathology: Traditional histopathological analysis involves staining tissue sections and examining them under a microscope to identify structural abnormalities and assess treatment responses.
Digital Pathology: This modern approach involves scanning tissue slides to create high-resolution digital images, enabling advanced image analysis and artificial intelligence (AI) applications in therapy development.